BRAT1 Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex) . The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
BAAT1; RMFSL; C7orf27
Swiss Prot
Q6PJG6
Reactivity
Human
Immunogen
Recombinant protein of human BRAT1
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
88 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of BRAT1 in K562 cell lysates using BRAT1 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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