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BMP4 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

ZYME; BMP2B; OFC11; BMP2B1; MCOPS6

Swiss Prot

P12644

Reactivity

Human

Immunogen

A synthetic peptide of human BMP4

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

47 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of BMP4 in K562, Hela cell lysates using BMP4 antibody (1:500 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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