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EIF4A1 Recombinant Rabbit mAb

Product Specifications

Background

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I

Swiss Prot

P60842

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human eIF4A1

Conjugation

Unconjugated

Applications

WB, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

46 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of eIF4A1 in K562, C6,3T3, Hela cell lysates using eIF4A1 antibody (1:1000 diluted) .

Host or Source

Rabbit

CAS Number

9000-83-3

Available Sizes

Curated Selection

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