LIG1 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
DNA ligase 1
Swiss Prot
P18858
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human LIG1
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
102 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of LIG1 in Hela, A549, HL-60 using LIG1 antibody (1:1000 diluted)
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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