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SMARCA2 Recombinant Rabbit mAb

Product Specifications

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

BRM; SNF2; SWI2; hBRM; NCBRS; Sth1p; BAF190; SNF2L2; SNF2LA; hSNF2a

Swiss Prot

P51531

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human SMARCA2/BRM

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

190 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of SMARCA2/BRM in A549, HL-60, U2OS cell lysates using SMARCA2/BRM antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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