Cullin 1 Recombinant Rabbit mAb
Product Specifications
Background
Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346) . In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
CUL1
Swiss Prot
Q13616
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human Cullin 1
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Cullin 1/CUL-1 in K562, C6 cell lysates using Cullin 1/CUL-1 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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