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Cullin 1 Recombinant Rabbit mAb

Product Specifications

Background

Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346) . In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits.

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CUL1

Swiss Prot

Q13616

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human Cullin 1

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

90 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Cullin 1/CUL-1 in K562, C6 cell lysates using Cullin 1/CUL-1 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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