CD22 Recombinant Rabbit mAb
Product Specifications
Background
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
SIGLEC2; SIGLEC-2
Swiss Prot
P20273
Reactivity
Human
Immunogen
Recombinant protein of human CD22
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of CD22 in Raji, K562, Ramos cell lysates using CD22 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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