DBF4 Recombinant Rabbit mAb
Product Specifications
Background
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ASK; CHIF; DBF4A; ZDBF1
Swiss Prot
Q9UBU7
Reactivity
Human
Immunogen
A synthetic peptide of human DBF4
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000-1:10000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
77 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of DBF4 in Hela, Jurkat cell lysates using DBF4 antibody (1:500 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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