Nesprin3 Recombinant Rabbit mAb
Product Specifications
Background
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341
Swiss Prot
Q6ZMZ3
Reactivity
Human
Immunogen
Recombinant protein of human Nesprin3
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000-1:2000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
112 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Nesprin3 in Jurkat, Hela cell lysates using Nesprin3 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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