CGAS Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
Mb21d1; E330016A19Rik
Swiss Prot
Q8C6L5
Reactivity
Mouse
Immunogen
Recombinant protein of mouse cGAS
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
58 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from RAW 264.7 cells using db12482 at 1:1000.
Host or Source
Rabbit
Available Sizes
Curated Selection
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