BAP1 Recombinant Rabbit mAb
Product Specifications
Background
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
UCHL2; hucep-6; HUCEP-13
Swiss Prot
Q92560
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human BAP1
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of BAP1 in Hela, A549, HL-60, U2OS cell lysates using BAP1 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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