Artemin Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ART; EVN; NBN; ENOVIN
Swiss Prot
Q5T4W7
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human Artemin
Conjugation
Unconjugated
Applications
WB, IHC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
23 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Artemin in K562, Rat Brain, C6,3T3, Hela cell lysates using Artemin antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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