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CaMKII Recombinant Rabbit mAb

Product Specifications

Background

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CAMKA

Swiss Prot

Q9UQM7

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human CaMKII

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of CaMKII alpha in Rat Brain, Hela cell lysates using CaMKII alpha antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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