CaMKII beta Recombinant Rabbit mAb

Product Specifications

Background

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CAMKA

Swiss Prot

Q13554

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human CaMKII

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot (WB) analysis of CaMKII beta Recombinant Rabbit mAb at 1:500 dilution Lane1:H9C2 whole cell lysate (30ug) Lane2:BV2 whole cell lysate (30ug) Lane3:SHSY5Y whole cell lysate (30ug)