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Cleaved PARP1 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1

Swiss Prot

P09874

Reactivity

Human

Immunogen

A synthetic peptide of human Cleaved PARP1

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC, IP

Purity

Affinity Purification

Modification

Cleaved

Molecular Weight

89 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Cleaved PARP1 in K562 cell lysates using Cleaved PARP1 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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