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FTO Recombinant Rabbit mAb

Product Specifications

Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

GDFD; ALKBH9; BMIQ14

Swiss Prot

Q9C0B1

Reactivity

Human

Immunogen

A synthetic peptide of human FTO

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

58 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of FTO in Hela, Jurkat cell lysates using FTO antibody (1:500 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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