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IGFBP7 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a member of the insulin-like growth factor (IGF) -binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307) . [provided by RefSeq, Dec 2011]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1

Swiss Prot

Q16270

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human IGFBP7

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

29 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of IGFBP7 in K562, Hela cell lysates using IGFBP7 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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