Integrin alpha V Recombinant Rabbit mAb
Product Specifications
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
CD51; MSK8; VNRA; VTNR
Swiss Prot
P06756
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human Integrin alpha V
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
130 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Integrin alphaV in C6, Hela cell lysates using Integrin alphaV antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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