Neurofilament heavy polypeptide Recombinant Rabbit mAb
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
NFH; CMT2CC
Swiss Prot
P12036
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human Neurofilament heavy polypeptide
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
180-220 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Neurofilament heavy polypeptide in mouse brain using Neurofilament heavy polypeptide antibody.
Host or Source
Rabbit
Available Sizes
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