P2Y12 Recombinant Rabbit mAb
Product Specifications
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T (AC) ; P2Y (AC) ; P2Y (12) R; P2Y (ADP) ; P2Y (cyc)
Swiss Prot
Q9H244
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human P2Y12
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of P2Y12 in A549, HL-60, U251, U87-MG cell lysates using P2Y12 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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