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P2Y12 Recombinant Rabbit mAb

Product Specifications

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8) . Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T (AC) ; P2Y (AC) ; P2Y (12) R; P2Y (ADP) ; P2Y (cyc)

Swiss Prot

Q9H244

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human P2Y12

Conjugation

Unconjugated

Applications

WB, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

52 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of P2Y12 in A549, HL-60, U251, U87-MG cell lysates using P2Y12 antibody (1:1000 diluted) .

Host or Source

Rabbit

CAS Number

9000-83-3

Available Sizes

Curated Selection

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