PAI1 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
PAI; PAI1; PAI-1; PLANH1
Swiss Prot
P05121
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PAI1
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot (WB) analysis of PAI1 Recombinant Rabbit mAb at 1:500 dilution Lane1:COS-7 whole cell lysate (30ug) Lane2:U251 whole cell lysate (30ug) Lane3:A549 whole cell lysate (30ug)
Host or Source
Rabbit
CAS Number
9000-83-3
Available Sizes
Curated Selection
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