SPAK Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
DCHT; PASK; SPAK
Swiss Prot
Q9UEW8
Reactivity
Human
Immunogen
A synthetic peptide of human SPAK
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
65 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from HCT116 cells using BS45199 at 1: 1000.
Host or Source
Rabbit
Available Sizes
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