Phospho-SMAD5 (Ser463/Ser465) Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
DWFC; JV5-1; MADH5
Swiss Prot
Q99717
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human SMAD5
Conjugation
Unconjugated
Applications
WB, ICC/IF
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from HeLa cells using BS43340 at 1: 1000.
Host or Source
Rabbit
Available Sizes
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