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Phospho-ULK1 (Ser467) Recombinant Rabbit mAb

Product Specifications

Background

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR.

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

ATG1; ATG1A; UNC51; hATG1; Unc51.1

Swiss Prot

O75385

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser467 of human ULK1

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:1000

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

130 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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