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Phospho-Tau (Ser422) Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103

Swiss Prot

P10636

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser422 of human Tau

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:2000

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

50-80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Host or Source

Rabbit

Available Sizes

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