Phospho-PDGF Receptor beta (Tyr740) Recombinant Rabbit mAb
Product Specifications
Background
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
Pdgfr; CD140b; PDGFR-1; AI528809
Swiss Prot
P05622
Reactivity
Mouse, Rat
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr740 of mouse PDGF Receptor beta
Conjugation
Unconjugated
Applications
WB, ICC/IF
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
190 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Host or Source
Rabbit
Available Sizes
Curated Selection
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