Phospho-p95 NBS1 (Ser432) Recombinant Rabbit mAb
Product Specifications
Background
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ATV; NBS; P95; NBS1; AT-V1; AT-V2
Swiss Prot
O60934
Reactivity
Human, Mouse
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser432 of human p95 NBS1
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC: 1:100
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
85 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Host or Source
Rabbit
Available Sizes
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