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Phospho-MSK1 (Ser376) Recombinant Rabbit mAb

Product Specifications

Background

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

MSK1; RLPK; MSPK1

Swiss Prot

O75582

Reactivity

Human, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser376 of human MSK1

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, IP

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

90 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Phospho-MSK1 (Ser376) in K562 cell lysates using Phospho-MSK1 (Ser376) antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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