Phospho-eIF4E (Ser209) Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
Swiss Prot
P06730
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of eIF4E (Phospho-Ser209) in K562, Rat Brain, C6,3T3 cell lysates using eIF4E (Phospho-Ser209) antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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