Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
PAKalpha
Swiss Prot
O75914
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser144 of human PAK1
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
61 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of PAK1 (Phospho-Ser144) /PAK2 (Phospho-Ser141) /PAK3 (Phospho-Ser154) in C6,3T3, Hela cell lysates using PAK1 (Phospho-Ser144) /PAK2 (Phospho-Ser141) /PAK3 (Phospho-Ser154) antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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