Phospho-LAT (Tyr200) Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
LAT1; pp36; IMD52
Swiss Prot
O43561
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr200 of human LAT
Conjugation
Unconjugated
Applications
WB, ICC/IF
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
36-38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Phospho-LAT (Tyr200) in Jurkat cell lysates using Phospho-LAT (Tyr200) antibody (1:500 diluted) .
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2580069 100 µg
GST3/GST pi/GSTP1 Rabbit Polyclonal Antibody (HRP)
Sign In for Pricing
View Details