Phospho-CD3 zeta (Tyr142) Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
Swiss Prot
P20963
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr142 of human CD3 zeta
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Phospho-CD3 zeta (Tyr142) in Jurkat cell lysates using Phospho-CD3 zeta (Tyr142) antibody (1:500 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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