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Phospho-CDK2 (Thr14) Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CDKN2; p33 (CDK2)

Swiss Prot

P24941

Reactivity

Human, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Thr14 of human Cdk2

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, IP

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

34 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Cdk2 (phospho-Thr14) in Hela, A549, HL-60, U2OS using Cdk2 (phospho-Thr14) antibody (1:1000 diluted)

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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