Phospho-Ezrin/Radixin/Moesin (Thr567/Thr564/Thr558) Recombinant Rabbit mAb
Product Specifications
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
CVL; CVIL; VIL2; HEL-S-105
Swiss Prot
P15311, P26038, P35241
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr567 of human Ezrin
Conjugation
Unconjugated
Applications
WB, IHC, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
75,80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Ezrin (phospho-Thr567) / Radixin (phospho-Thr564) / Moesin (phospho-Thr558) in Hela, CHO-K1, C6 using Ezrin (phospho-Thr567) / Radixin (phospho-Thr564) / Moesin (phospho-Thr558) antibody (1:1000 diluted)
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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