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Phospho-Ezrin/Radixin/Moesin (Thr567/Thr564/Thr558) Recombinant Rabbit mAb

Product Specifications

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CVL; CVIL; VIL2; HEL-S-105

Swiss Prot

P15311, P26038, P35241

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Thr567 of human Ezrin

Conjugation

Unconjugated

Applications

WB, IHC, IP

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

75,80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Ezrin (phospho-Thr567) / Radixin (phospho-Thr564) / Moesin (phospho-Thr558) in Hela, CHO-K1, C6 using Ezrin (phospho-Thr567) / Radixin (phospho-Thr564) / Moesin (phospho-Thr558) antibody (1:1000 diluted)

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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