Phospho-IKB alpha (Ser32) Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
IKBA; MAD-3; NFKBI
Swiss Prot
P25963
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser32 of human IKB alpha
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of IKB alpha (Phospho-Ser32) in 3T3, Hela cell lysates using IKB alpha (Phospho-Ser32) antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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