Phospho-IRE1 (Ser724) Recombinant Rabbit mAb
Product Specifications
Background
Serine/threonine-protein kinase and endoribonuclease that acts as a key sensor for the endoplasmic reticulum unfolded protein response (UPR) (PubMed:11779464, PubMed:11175748, PubMed:12637535, PubMed:9637683, PubMed:21317875)
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
IRE1b; IRE2p; hIRE2p; IRE1-BETA
Swiss Prot
O75460
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of IRE1 (phospho-Ser724) in MCF-7, HL-60 cell lysates using IRE1 (phospho-Ser724) antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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