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Phospho-MEK1 (Ser298) Recombinant Rabbit mAb

Product Specifications

Background

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CFC3; MEK1; MKK1; MAPKK1; PRKMK1

Swiss Prot

Q02750

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser298 of human MEK1

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Phospho-MEK1 (Ser298) in C6,3T3, Hela cell lysates using Phospho-MEK1 (Ser298) antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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