Phospho-mTOR (Ser2448) Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
SKS; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Swiss Prot
P42345
Reactivity
Human, Mouse
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
Conjugation
Unconjugated
Applications
WB, IHC
Purity
Affinity Purification
Modification
Phosphorylated
Molecular Weight
289 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from T24 cells using BS43025 at 1: 1000.
Host or Source
Rabbit
Available Sizes
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