HDAC1 Recombinant Rabbit mAb
Product Specifications
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
HD1; RPD3; GON-10; RPD3L1
Swiss Prot
Q13547
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HDAC1
Conjugation
Unconjugated
Applications
WB
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
62 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of HDAC1 in K562 cell lysates using HDAC1 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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