NBN mouse monoclonal antibody

Product Specifications

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

AT-V1; AT-V2; ATV; NBS; NBS1; P95

Swiss Prot

O60934

Reactivity

Human, Monkey

Immunogen

Human recombinant protein fragment corresponding to amino acids 461-754 of human NBN (NP_002476) produced in E.coli.

Conjugation

Unconjugated

Applications

10k-ChIP, IF, IHC, WB

Dilution

IHC 1:100, IF 1:100

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .