KRT8/CK8 mouse monoclonal antibody
Product Specifications
Background
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Swiss Prot
P05787
Reactivity
Human, Monkey, Mouse, Rat
Immunogen
Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Conjugation
Unconjugated
Applications
10k-ChIP, IF, IHC, WB
Dilution
WB 1:500~1000, IHC 1:50, IF 1:50~100
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
53.5 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Host or Source
Mouse
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY419037 100 µg
Retinoblastoma binding protein 1 (ARID4A) (NM_002892) Human Over-expression Lysate
Sign In for Pricing
View Details