PAPSS2 mouse monoclonal antibody

Product Specifications

Background

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

ATPSK2; BCYM4; SK2

Swiss Prot

O95340

Reactivity

Human, Mouse, Rat

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-247 of human PAPSS2 (NP_004661) produced in E.coli.

Conjugation

Unconjugated

Applications

IHC, WB

Dilution

WB 1:2000, IHC 1:150

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .