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OTUB1 mouse monoclonal antibody

Product Specifications

Background

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

HSPC263; OTB1; OTU1

Swiss Prot

Q96FW1

Reactivity

Human, Rat

Immunogen

Full length human recombinant protein of human OTUB1 (NP_060140) produced in HEK293T cell.

Conjugation

Unconjugated

Applications

FC, IHC, WB

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

31.1 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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