UNG mouse monoclonal antibody

Product Specifications

Background

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15

Swiss Prot

P13051

Reactivity

Human, Mouse, Rat

Immunogen

Full length human recombinant protein of human UNG (NP_550433) produced in HEK293T cell.

Conjugation

Unconjugated

Applications

IF, IHC, WB

Dilution

WB 1:500~2000, IHC 1:150, IF 1:100

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .