UNG mouse monoclonal antibody
Product Specifications
Background
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15
Swiss Prot
P13051
Reactivity
Human, Mouse, Rat
Immunogen
Full length human recombinant protein of human UNG (NP_550433) produced in HEK293T cell.
Conjugation
Unconjugated
Applications
IF, IHC, WB
Dilution
WB 1:500~2000, IHC 1:150, IF 1:100
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
34.5 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG2b
Host or Source
Mouse
Available Sizes
Curated Selection
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