LMAN1 mouse monoclonal antibody
Product Specifications
Background
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Swiss Prot
P49257
Reactivity
Human, Dog, Rat, Monkey, Mouse
Immunogen
Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.
Conjugation
Unconjugated
Applications
FC, IF, IHC, WB
Dilution
WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
54.2 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Host or Source
Mouse
Available Sizes
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