CDX2 mouse monoclonal antibody

Product Specifications

Background

The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CDX-3; CDX2/AS; CDX3

Swiss Prot

Q99626

Reactivity

Human, Dog, Mouse, Rat

Immunogen

Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2

Conjugation

Unconjugated

Applications

IF, WB

Dilution

WB 1:1000

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .