CDX2 mouse monoclonal antibody
Product Specifications
Background
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CDX-3; CDX2/AS; CDX3
Swiss Prot
Q99626
Reactivity
Human, Dog, Mouse, Rat
Immunogen
Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Conjugation
Unconjugated
Applications
IF, WB
Dilution
WB 1:1000
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
33.5 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG2a
Host or Source
Mouse
Available Sizes
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