Phospho-MEK1-S298 polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CFC3; MAPKK1; MEK1; MKK1; PRKMK1; MAP2K1

Swiss Prot

Q02750

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphorylated peptide around S298 of human MEK1 (NP_002746.1) .

Conjugation

Unconjugated

Applications

WB, IP

Dilution

WB,1:500 - 1:2000|IP,1:50 - 1:100

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .