GTF3C4 polyclonal antibody

Product Specifications

Background

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

GTF3C4; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA

Swiss Prot

Q9UKN8

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein of human GTF3C4 (NP_036336.2) .

Conjugation

Unconjugated

Applications

WB, IHC, IF/ICC

Dilution

WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .